CD40L (CD40LG) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Glu108-Leu261
Tag	N-6His-Avi
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Note	Biotinylated Recombinant Human CD40 Ligand is produced by our Mammalian expression system and the target gene encoding Glu108-Leu261 is expressed with a 6His, Avi tag at the N-terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	959
UniProt ID	P29965
Summary	CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer in membrane bound and soluble form, both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.