HIV Recombinant Protein

Specifications

Product Data
Species	HIV
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met1-Glu498
Tag	C-8His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note	Recombinant HIV 1 Envelope glycoprotein gp120 is produced by our Mammalian expression system and the target gene encoding Met1-Glu498 is expressed with a 8His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Summary	Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.

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