Fcgrt Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ser22-Val301&Ile21-Met119
Tag	C-His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note	Recombinant Mouse IgG Fc fragment receptor transporter is produced by our Mammalian expression system and the target gene encoding Ser22-Val301&Ile21-Met119 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	14132
UniProt ID	Q61559
Summary	FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51（alpha chain) and Beta-2-microglobulin（Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).

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