Escherichia coli Recombinant Protein

Specifications

Product Data
Species	Escherichia coli
Protein Source	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) M1-G408
Buffer	Supplied as a 0.2 um filtered solution of 20mM HEPES, 300mM NaCl,10%glycerol, 2mM DTT,0.1mM EDTA,pH7.5.
Note	Recombinant E.coli RNA-splicing ligase RtcB is produced by E.coli. The target gene encoding M1-G408 is expressed.
Stability	12 months from date of despatch
Reference Data
Summary	RNA-splicing ligase RtcB is a member of RtcB family. It is a GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. RtcB rejoins broken stem-loops of tRNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. RtcB can also act as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases.

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