LAIR1 Human Recombinant Protein
CNY 1,650.00
货期*
2周
规格
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经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Protein Source | Human 293 |
Expression cDNA Clone or AA Sequence |
Q22-Y165
|
Tag | C-mFc |
Buffer | Lyophilized from a 0.2 um filtered solution of 2umM PB, 15umM NaCl, pH 7.2 |
Note | Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 1 is produced by human 293 cells. The target gene encoding Gln22-Tyr165 is expressed with a 6His tag at the C-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 3903 |
UniProt ID | Q6GTX8 |
Summary | Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) is a type I transmembrane glycoprotein, that belongs to immunoglobulin superfamily and leukocyte-associated inhibitory receptor family. LAIR-1 is expressed on most of the mononuclear cells, including natural killer (NK) cells, B-cells, T-cells, monocytes, and dendritic cells. LAIR-1 plays a role in negatively regulating the cytolytic function of immune cells to prevent lysis of cells recognized as self. Studies predicted that LAIR-1 mediates the inhibitory function based on immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic domain. |
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