PLGF (PGF) (NM_002632) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Human PLGF, the region of Ala21-Arg149, from gene Accession# NM_002632
Tag	Tag Free
Predicted MW	14.5 kDa
Concentration	lot specific
Purity	>95%, as determined by Coomassie stained SDS-PAGE.
Buffer	5 mM citric acid, 0.15 M NaCl, 5 mM NaHPO4, pH 4.0
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	The ED50 is 1-3 ng/ml, corresponding to a specific activity of 0.33 - 1 x 106 units/mg, determined by the dose dependent binding to VEGFR1-Fc chimera using a functional ELISA.
Endotoxin	Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq	NP_002623
Locus ID	5228
UniProt ID	P49763, Q53XY6, Q86TW6
Refseq Size	1758
Cytogenetics	14q24.3
Refseq ORF	510
Synonyms	D12S1900; PGFL; PIGF; PLGF; PlGF-2; SHGC-10760
Summary	This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Bladder cancer, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma

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