Pf4 (NM_019932) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Mouse CXCL4, the region of Val30-Ser105, from gene Accession# NM_019932
Tag	Tag Free
Predicted MW	8.2 kDa
Concentration	lot specific
Purity	>98%, as determined by Coomassie stained SDS-PAGE
Buffer	1 x PBS
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	Mouse CXCL4 inhibits the proliferation of HUVEC cells induced by recombinant human FGF-basic (Cat. No. TP723719). The ED50 for this effect is 0.8 – 4 µg/mL.
Endotoxin	Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq	NP_064316
Locus ID	56744
UniProt ID	Q9Z126, Q3TVN6, Q6P8R3
Refseq Size	525
Cytogenetics	5 E1
Refseq ORF	315
Synonyms	Cxcl4; Scyb4
Summary	Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation (By similarity).[UniProtKB/Swiss-Prot Function]

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