Insulin Receptor R (INSRR) (NM_014215) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	Sf9
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) A DNA sequence from TrueORF clone, RC224956, encoding the region(Met-Ala747-His921) of Homo sapiens INSRR
Tag	C-DDK
Predicted MW	19.1 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_055030
Locus ID	3645
UniProt ID	P14616
Refseq Size	4148
Cytogenetics	1q23.1
Refseq ORF	3891
Synonyms	IRR
Summary	Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	Prostate cancer, Regulation of actin cytoskeleton

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