Thyroglobulin (TG) (NM_003235) Human Recombinant Protein

CAT#: TP701224-B

Purified recombinant protein of Human thyroglobulin (TG), Asn20-End, with C-terminal His and site-specific Biotinylation on the C-terminal AVI-plus tag, expressed in HEK293 cells, 50ug



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Avi-tag Biotinylated Protein
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CNY 7,820.00


货期*
2周

规格
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC216216, encoding the region(Asn20-End) of TG
Tag C-AVI-PLUS
Predicted MW 306.0 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity The biotin to protein ratio is 1 as determined by Streptavidin Pull-Down Assay.
Reference Data
RefSeq NP_003226
Locus ID 7038
UniProt ID P01266
Refseq Size 8453
Cytogenetics 8q24.22
Refseq ORF 8304
Synonyms AITD3; TGN
Summary Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
Protein Families Druggable Genome
Protein Pathways Autoimmune thyroid disease
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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