Mbnl3 (NM_134163) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR205132 protein sequence Red=Cloning site Green=Tags(s) MTPVNVALIRDTKWLTLEVCREFQRGTCSRADAECRFAHPPRVCHVENGRVVACFDSLKGRCTRENCKYL HPPPHLKSQLEVNGRNNLIQQKTAAAMFAQHMQLMLQNAQMSSLASFPMNPSLAANPAMAFNPYMTHPGM GLVPAELLPNGPVLISGNPPLALPGVPGPKPIRTDRLEVCREFQRGNCTRGESECRYAHPTDVSMIEVTD NSVTICMDYIKGRCSREKCKYFHPPPHLQAKLRAAHHQMNHSAANAMALPHGALQLIPKRSALDKANGAT PVFNPSVFHCQQALANMQIPQQAFIPTVPMMHGATPSTVSTATPPASNVPYVPTTTGNQLKY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	37.6 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_598924
Locus ID	171170
UniProt ID	Q8R003, Q542D8, Q8BYC7
Refseq Size	8671
Cytogenetics	X A5
Refseq ORF	1029
Synonyms	A530038J18Rik; AI661274; CHCR; E430034C16Rik; MBLX; MBLX39; MBXL
Summary	Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins (By similarity). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.[UniProtKB/Swiss-Prot Function]

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