SPINT2 / HAI2 (28-197, His-tag) Human Protein

Specifications

Product Data
Species	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) ADRERSIHDF CLVSKVVGRC RASMPRWWYN VTDGSCQLFV YGGCDGNSNN YLTKEECLKK CATVTENATG DLATSRNAAD SSVPSAPRRQ DSEDHSSDMF NYEEYCTANA VTGPCRASFP RWYFDVERNS CNNFIYGGCR GNKNSYRSEE ACMLRCFRQQ ENPPLPLGSK HHHHHH
Tag	His-tag
Predicted MW	20 kDa
Concentration	lot specific
Purity	>80% by SDS - PAGE.
Buffer	Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate buffered saline (pH 7.4), 10% glycerol.
Preparation	Liquid purified protein
Protein Description	Recombinant human SPINT2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Endotoxin	< 1.0 Eu per 1 microgram of protein (determined by LAL method)
Reference Data
RefSeq	NP_001159575
Locus ID	10653
UniProt ID	O43291, A0A140VJV6, B4DLU1
Cytogenetics	19q13.2
Synonyms	DIAR3; HAI-2; HAI2; Kop; PB
Summary	This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Protein Families	Transmembrane

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