SERPINE1 / PAI1 (Wild type) Mouse Protein
CAT#: AR31009PU-N
SERPINE1 / PAI1 (Wild type) mouse recombinant protein, 0.5 mg
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CNY 36,919.00
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规格
Cited in 4 publications. |
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Specifications
Product Data | |
Species | Mouse |
Expression Host | E. coli |
Predicted MW | 43 kDa |
Concentration | lot specific |
Purity | >98% by SDS-PAGE. 80 +/- 5% active by uPA titration. Purified by Column chromatography |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 0.05M Sodium Acetate, 0.1M Sodium Chloride, 1 mM EDTA, pH 5.0 without preservatives |
Preparation | Liquid purified protein |
Protein Description | Recombinant Human Plasminogen Activator Inhibitor 1 (PAI-1), wild type. Does not contain a fusion partner. |
Storage | Store (in aliquots) at -70°C Aliquot to avoid multiple freeze/thaw cycles. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_000593 |
Locus ID | 5054 |
UniProt ID | P05121, A0A024QYT5 |
Cytogenetics | 7q22.1 |
Synonyms | PAI; PAI-1; PAI1; PLANH1 |
Summary | This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Complement and coagulation cascades, p53 signaling pathway |
Citations (4)
The use of this Proteins has been cited in the following citations: |
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Silencing of Ago-2 Interacting Protein SERBP1 Relieves KCC2 Repression by miR-92 in Neurons
,null,
Cells
,PubMed ID 35326503
[SERPINE1]
|
Alteration in global DNA methylation status following preconditioning injury influences axon growth competence of the sensory neurons.
,null,
Experimental neurology
,PubMed ID 31926166
[SERPINE1]
|
Mineralocorticoid Receptor (MR) trans-Activation of Inflammatory AP-1 Signaling
,null,
The Journal of Biological Chemistry
,PubMed ID 27650495
[SERPINE1]
|
Redox regulation of soluble epoxide hydrolase by 15-deoxy-?-prostaglandin J2 controls coronary hypoxic vasodilation
,null,
Circulation Research
,PubMed ID 21164107
[SERPINE1]
|
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