Cyfra-21-1 Human Protein

Specifications

Product Data
Description	Cyfra-21-1 human protein, 50 µg
Species	Human
Protein Source	Cell culture
Concentration	lot specific
Purity	Ion Exchange Chromatography
Buffer	Presentation State: Purified State: Calibrator grade, liquid (0.2µm filtered) Buffer System: PBS, pH 7.4 without preservatives
Preparation	Calibrator grade, liquid (0.2µm filtered)
Protein Description	Cyfra-21-1 Antigen Cyfra-21-1, Cytokeratin 19 Fragment, Low Cross-reactivity (LCR) Calibrator grade.  Known contaminants: Centocor CA125 RIA = 408.3 Units/ml (1.2%) Elecsys 15-3 Assay = 5.85 Units/ml (< 0.1%) Centocor CA19-9 RIA = 15.81 Units/ml (< 0.1%).
Note	Caution: Cell line supernatant has tested negative for HIV1, HIV2, HCV antibodies, HBsAg and HIV Ag. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
Storage	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
Locus ID	109864281
Cytogenetics	21p11.2
Synonyms	RNA5-8N2
Summary	45S ribosomal DNA (rDNA) arrays, or clusters, are present on human chromosomes 13, 14, 15, 21 and 22, designated RNR1 through RNR5, respectively. Each cluster consists of multiple 45S rDNA repeat units that vary in number among individuals and chromosomes, with total diploid copy number estimates ranging from 60 to >800 repeat units in a human genome. The 45S rDNA repeat unit encodes a 45S rRNA precursor, transcribed by RNA polymerase I, which is processed to form the 18S, 5.8S and 28S rRNAs. This gene represents a copy of the 5.8S ribosomal RNA on chromosome 21. [provided by RefSeq, Mar 2017]

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