Poliovirus Receptor (PVR) (NM_001135769) Human Mass Spec Standard

CAT#: PH327222

PVR MS Standard C13 and N15-labeled recombinant protein (NP_001129241)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Transient overexpression lysate of poliovirus receptor (PVR), transcript variant 1
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Specifications

Product Data
Description PVR MS Standard C13 and N15-labeled recombinant protein (NP_001129241)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC227222
Predicted MW 39.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001129241
RefSeq ORF 1092
Synonyms CD155; HVED; Necl-5; NECL5; PVS; TAGE4
Locus ID 5817
Cytogenetics 19q13.31
Summary The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
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