NFAT1 (NFATC2) (NM_001136021) Human Mass Spec Standard

CAT#: PH326803

NFATC2 MS Standard C13 and N15-labeled recombinant protein (NP_001129493)



  View other "NFAT1" proteins (9)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description NFATC2 MS Standard C13 and N15-labeled recombinant protein (NP_001129493)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226803
Predicted MW 97.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001129493
RefSeq ORF 2703
Synonyms NFAT1; NFATP
Locus ID 4773
Cytogenetics 20q13.2
Summary This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Axon guidance, B cell receptor signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
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