DIABLO (NM_138929) Human Mass Spec Standard

CAT#: PH324190

DIABLO MS Standard C13 and N15-labeled recombinant protein (NP_620307)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description DIABLO MS Standard C13 and N15-labeled recombinant protein (NP_620307)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC224190
Predicted MW 15.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_620307
RefSeq Size 1366
RefSeq ORF 585
Synonyms DFNA64; DIABLO-S; SMAC; SMAC3
Locus ID 56616
Cytogenetics 12q24.31
Summary This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Protein Families Transmembrane
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