HIP55 (DBNL) (NM_001014436) Human Mass Spec Standard

CAT#: PH323992

DBNL MS Standard C13 and N15-labeled recombinant protein (NP_001014436)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description DBNL MS Standard C13 and N15-labeled recombinant protein (NP_001014436)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223992
Predicted MW 48.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001014436
RefSeq Size 2210
RefSeq ORF 1293
Synonyms ABP1; HIP-55; HIP55; SH3P7
Locus ID 28988
Cytogenetics 7p13
Summary Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.[UniProtKB/Swiss-Prot Function]
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