ABL2 (NM_001100108) Human Mass Spec Standard

CAT#: PH322989

ABL2 MS Standard C13 and N15-labeled recombinant protein (NP_001093578)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (ABL2), transcript variant b
    • 100 ug

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Specifications

Product Data
Description ABL2 MS Standard C13 and N15-labeled recombinant protein (NP_001093578)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC222989
Predicted MW 126.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001093578
RefSeq Size 11927
RefSeq ORF 3501
Synonyms ABLL; ARG; FLJ22224; FLJ31718; FLJ41441
Locus ID 27
Cytogenetics 1q25.2
Summary This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways ErbB signaling pathway, Viral myocarditis
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