PTPRS (NM_130854) Human Mass Spec Standard

CAT#: PH321495

PTPRS MS Standard C13 and N15-labeled recombinant protein (NP_570924)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description PTPRS MS Standard C13 and N15-labeled recombinant protein (NP_570924)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221495
Predicted MW 209.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_570924
RefSeq Size 6386
RefSeq ORF 5730
Synonyms PTPSIGMA; R-PTP-S; R-PTP-sigma
Locus ID 5802
Cytogenetics 19p13.3
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Phosphatase, Transmembrane
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