SNRPN (NM_022805) Human Mass Spec Standard

CAT#: PH320680

SNRPN MS Standard C13 and N15-labeled recombinant protein (NP_073716)



  View other "SNRPN" proteins (11)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Rabbit Polyclonal Anti-SNRPN Antibody
    • 100 ug

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Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Description SNRPN MS Standard C13 and N15-labeled recombinant protein (NP_073716)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220680
Predicted MW 24.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_073716
RefSeq Size 1605
RefSeq ORF 720
Synonyms HCERN3; PWCR; PWS; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNURF-SNRPN
Locus ID 6638
Cytogenetics 15q11.2
Summary This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]
Protein Families Stem cell - Pluripotency
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