DYNLL1 (NM_001037495) Human Mass Spec Standard

CAT#: PH318700

DYNLL1 MS Standard C13 and N15-labeled recombinant protein (NP_001032584)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description DYNLL1 MS Standard C13 and N15-labeled recombinant protein (NP_001032584)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218700
Predicted MW 10.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001032584
RefSeq Size 747
RefSeq ORF 267
Synonyms DLC1; DLC8; DNCL1; DNCLC1; hdlc1; LC8; LC8a; PIN
Locus ID 8655
Cytogenetics 12q24.31
Summary Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
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