ENTPD8 (NM_001033113) Human Mass Spec Standard

Specifications

Product Data
Description	ENTPD8 MS Standard C13 and N15-labeled recombinant protein (NP_001028285)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC218598
Predicted MW	53.7 kDa
Protein Sequence	Sequence Link (showhide) >RC218598 representing NM_001033113 Red=Cloning site Green=Tags(s) MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTG VVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR DIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGAS TQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQT TLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFY AFSNFYYTFHFLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFS EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQL FWLQD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001028285
RefSeq Size	2222
RefSeq ORF	1485
Synonyms	E-NTPDase; GLSR2492; NTPDase-8; UNQ2492
Locus ID	377841
Cytogenetics	9q34.3
Summary	Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP.[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane
Protein Pathways	Purine metabolism, Pyrimidine metabolism

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