CACNB1 (NM_199247) Human Mass Spec Standard

CAT#: PH317910

CACNB1 MS Standard C13 and N15-labeled recombinant protein (NP_954855)



  View other "CACNB1" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 1
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Specifications

Product Data
Description CACNB1 MS Standard C13 and N15-labeled recombinant protein (NP_954855)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217910
Predicted MW 57.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_954855
RefSeq Size 1847
RefSeq ORF 1569
Synonyms CAB1; CACNLB1; CCHLB1
Locus ID 782
Cytogenetics 17q12
Summary The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Ion Channels: Other
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway
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