BDNF (NM_170734) Human Mass Spec Standard

CAT#: PH317124

BDNF MS Standard C13 and N15-labeled recombinant protein (NP_733930)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description BDNF MS Standard C13 and N15-labeled recombinant protein (NP_733930)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217124
Predicted MW 25.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_733930
RefSeq Size 3958
RefSeq ORF 786
Synonyms ANON2; BULN2
Locus ID 627
Cytogenetics 11p14.1
Summary This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Transmembrane
Protein Pathways Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway
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