UBE2E1 (NM_182666) Human Mass Spec Standard

Specifications

Product Data
Description	UBE2E1 MS Standard C13 and N15-labeled recombinant protein (NP_872607)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC214934
Predicted MW	19.3 kDa
Protein Sequence	Sequence Link (showhide) >RC214934 representing NM_182666 Red=Cloning site Green=Tags(s) MSDDDSRASTSSSSSSSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKSAGPKGDNIYEWRSTILGPP GSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLT DCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYAT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_872607
RefSeq Size	1428
RefSeq ORF	528
Synonyms	UBCH6
Locus ID	7324
Cytogenetics	3p24.2
Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Protein Pathways	Ubiquitin mediated proteolysis

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