PAX8 (NM_013953) Human Mass Spec Standard

CAT#: PH314188

PAX8 MS Standard C13 and N15-labeled recombinant protein (NP_039247)



  View other "PAX8" proteins (15)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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经常一起买 (2)
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Transient overexpression lysate of paired box 8 (PAX8), transcript variant PAX8A
    • 100 ug

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Specifications

Product Data
Description PAX8 MS Standard C13 and N15-labeled recombinant protein (NP_039247)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214188
Predicted MW 34.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_039247
RefSeq Size 3755
RefSeq ORF 963
Locus ID 7849
Cytogenetics 2q14.1
Summary This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Thyroid cancer
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