Cytochrome P450 17A1 (CYP17A1) (NM_000102) Human Mass Spec Standard

CAT#: PH309042

CYP17A1 MS Standard C13 and N15-labeled recombinant protein (NP_000093)



  View other "Cytochrome P450 17A1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1)
    • 100 ug

CNY 3,080.00


CYP17A1 mouse monoclonal antibody, clone OTI3F11 (formerly 3F11)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Description CYP17A1 MS Standard C13 and N15-labeled recombinant protein (NP_000093)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209042
Predicted MW 57.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000093
RefSeq Size 1755
RefSeq ORF 1524
Synonyms CPT7; CYP17; P450C17; S17AH
Locus ID 1586
Cytogenetics 10q24.32
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, P450
Protein Pathways C21-Steroid hormone metabolism, Metabolic pathways
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