ROR beta (RORB) (NM_006914) Human Mass Spec Standard

Specifications

Product Data
Description	RORB MS Standard C13 and N15-labeled recombinant protein (NP_008845)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208666
Predicted MW	52.1 kDa
Protein Sequence	Sequence Link (showhide) >RC208666 protein sequence Red=Cloning site Green=Tags(s) MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKC LALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQSGEAEALARVYSSSISNGLSNLNNETSGT YANGHVIDLPKSEGYYNVDSGQPSPDQSGLDMTGIKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMT EIDRIAQNIIKSHLETCQYTMEELHQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRI TGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLC SLQLTEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTITAVC NLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCATGCK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_008845
RefSeq Size	3604
RefSeq ORF	1377
Synonyms	bA133M9.1; EIG15; NR1F2; ROR-BETA; RZR-BETA; RZRB
Locus ID	6096
Cytogenetics	9q21.13
Summary	The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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