HMGCS2 (NM_005518) Human Mass Spec Standard

CAT#: PH308128

HMGCS2 MS Standard C13 and N15-labeled recombinant protein (NP_005509)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description HMGCS2 MS Standard C13 and N15-labeled recombinant protein (NP_005509)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208128
Predicted MW 56.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005509
RefSeq Size 2477
RefSeq ORF 1524
Locus ID 3158
Cytogenetics 1p12
Summary The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Protein Families Druggable Genome
Protein Pathways Butanoate metabolism, Metabolic pathways, PPAR signaling pathway, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Valine, leucine and isoleucine degradation
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