CRY2 (NM_021117) Human Mass Spec Standard

CAT#: PH307337

CRY2 MS Standard C13 and N15-labeled recombinant protein (NP_066940)



  View other "CRY2" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CRY2 MS Standard C13 and N15-labeled recombinant protein (NP_066940)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207337
Predicted MW 66.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_066940
RefSeq Size 4204
RefSeq ORF 1779
Synonyms HCRY2; PHLL2
Locus ID 1408
Cytogenetics 11p11.2
Summary This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
Protein Families Druggable Genome
Protein Pathways Circadian rhythm - mammal
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