OGT (NM_181672) Human Mass Spec Standard

CAT#: PH306822

OGT MS Standard C13 and N15-labeled recombinant protein (NP_858058)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Rabbit Polyclonal antibody to O-GlcNAc transferase (O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase))
    • 100 ul

CNY 6,281.00

Specifications

Product Data
Description OGT MS Standard C13 and N15-labeled recombinant protein (NP_858058)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206822
Predicted MW 116.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_858058
RefSeq Size 5475
RefSeq ORF 3138
Synonyms HINCUT-1; HRNT1; MRX106; O-GLCNAC; OGT1
Locus ID 8473
Cytogenetics Xq13.1
Summary This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, O-Glycan biosynthesis
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