ATP6V1B2 (NM_001693) Human Mass Spec Standard

CAT#: PH305447

ATP6V1B2 MS Standard C13 and N15-labeled recombinant protein (NP_001684)



  View other "ATP6V1B2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ATP6V1B2)
    • 100 ug

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ATP6V1B2 mouse monoclonal antibody, clone OTI1E11 (formerly 1E11)
    • 100 ul

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Specifications

Product Data
Description ATP6V1B2 MS Standard C13 and N15-labeled recombinant protein (NP_001684)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205447
Predicted MW 56.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001684
RefSeq Size 3054
RefSeq ORF 1533
Synonyms ATP6B1B2; ATP6B2; DOOD; HO57; VATB; Vma2; VPP3; ZLS2
Locus ID 526
Cytogenetics 8p21.3
Summary This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection
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