MALT1 (NM_173844) Human Mass Spec Standard

CAT#: PH304322

MALT1 MS Standard C13 and N15-labeled recombinant protein (NP_776216)



  View other "MALT1" proteins (7)

Need it in bulk or customized?
Get a free quote

CNY 14,250.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (2)
MALT1 mouse monoclonal antibody, clone OTI3A2
    • 100 ul

CNY 1,999.00
CNY 2,700.00


Transient overexpression lysate of mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1), transcript variant 1
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Description MALT1 MS Standard C13 and N15-labeled recombinant protein (NP_776216)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204322
Predicted MW 90.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_776216
RefSeq Size 4996
RefSeq ORF 2439
Synonyms IMD12; MLT; MLT1; PCASP1
Locus ID 10892
Cytogenetics 18q21.32
Summary This gene encodes a caspase-like protease that plays a role in BCL10-induced activation of NF-kappaB. The protein is a component of the CARMA1-BCL10-MALT1 (CBM) signalosome that triggers NF-kappaB signaling and lymphoctye activation following antigen-receptor stimulation. Mutations in this gene result in immunodeficiency 12 (IMD12). This gene has been found to be recurrently rearranged in chromosomal translocations with other genes in mucosa-associated lymphoid tissue lymphomas, including a t(11;18)(q21;q21) translocation with the baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) locus [BIRC3(API2)-MALT1], and a t(14;18)(q32;q21) translocation with the immunoglobulin heavy chain locus (IGH-MALT1). Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2018]
Protein Families Druggable Genome, Protease
Protein Pathways B cell receptor signaling pathway, T cell receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...