Glutamine Synthetase (GLUL) (NM_001033056) Human Mass Spec Standard

CAT#: PH304039

GLUL MS Standard C13 and N15-labeled recombinant protein (NP_001028228)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
GLUL mouse monoclonal antibody, clone OTI1F4 (formerly 1F4)
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Transient overexpression lysate of glutamate-ammonia ligase (glutamine synthetase) (GLUL), transcript variant 1
    • 100 ug

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Specifications

Product Data
Description GLUL MS Standard C13 and N15-labeled recombinant protein (NP_001028228)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204039
Predicted MW 42.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001028228
RefSeq Size 4083
RefSeq ORF 1119
Synonyms GLNS; GS; PIG43; PIG59
Locus ID 2752
Cytogenetics 1q25.3
Summary The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Protein Pathways Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways, Nitrogen metabolism
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