LTA (NM_000595) Human Mass Spec Standard

CAT#: PH303741

LTA MS Standard C13 and N15-labeled recombinant protein (NP_000586)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description LTA MS Standard C13 and N15-labeled recombinant protein (NP_000586)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203741
Predicted MW 22.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000586
RefSeq Size 1423
RefSeq ORF 615
Synonyms LT; TNFB; TNFSF1; TNLG1E
Locus ID 4049
Cytogenetics 6p21.33
Summary The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Antigen processing and presentation, Cytokine-cytokine receptor interaction, Type I diabetes mellitus
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