Seladin 1 (DHCR24) (NM_014762) Human Mass Spec Standard

CAT#: PH303507

DHCR24 MS Standard C13 and N15-labeled recombinant protein (NP_055577)



  View other "Seladin 1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description DHCR24 MS Standard C13 and N15-labeled recombinant protein (NP_055577)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203507
Predicted MW 60.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_055577
RefSeq Size 4286
RefSeq ORF 1548
Synonyms DCE; Nbla03646; seladin-1; SELADIN1
Locus ID 1718
Cytogenetics 1p32.3
Summary This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Stem cell - Pluripotency, Transmembrane
Protein Pathways Metabolic pathways, Steroid biosynthesis
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