CKS1 (CKS1B) (NM_001826) Human Mass Spec Standard

Specifications

Product Data
Description	CKS1B MS Standard C13 and N15-labeled recombinant protein (NP_001817)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202933
Predicted MW	9.7 kDa
Protein Sequence	Sequence Link (showhide) >RC202933 protein sequence Red=Cloning site Green=Tags(s) MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFR RPLPKKPKK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001817
RefSeq Size	834
RefSeq ORF	237
Synonyms	CKS1; ckshs1; PNAS-16; PNAS-18
Locus ID	1163
Cytogenetics	1q21.3
Summary	CKS1B protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein. [provided by RefSeq, Sep 2008]
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Pathways in cancer, Small cell lung cancer

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