SM22 alpha (TAGLN) (NM_001001522) Human Mass Spec Standard

CAT#: PH302448

TAGLN MS Standard C13 and N15-labeled recombinant protein (NP_001001522)



  View other "SM22 alpha" proteins (7)

Need it in bulk or customized?
Get a free quote

CNY 19,520.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (2)
TAGLN mouse monoclonal antibody, clone OTI8C8 (formerly 8C8)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


Transient overexpression lysate of transgelin (TAGLN), transcript variant 2
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Description TAGLN MS Standard C13 and N15-labeled recombinant protein (NP_001001522)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202448
Predicted MW 22.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001001522
RefSeq Size 1574
RefSeq ORF 603
Synonyms SM22; SM22-alpha; SMCC; TAGLN1; WS3-10
Locus ID 6876
Cytogenetics 11q23.3
Summary This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...