IKB beta (NFKBIB) (NM_002503) Human Mass Spec Standard

CAT#: PH302182

NFKBIB MS Standard C13 and N15-labeled recombinant protein (NP_002494)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description NFKBIB MS Standard C13 and N15-labeled recombinant protein (NP_002494)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202182
Predicted MW 37.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002494
RefSeq Size 1243
RefSeq ORF 1068
Synonyms IKBB; TRIP9
Locus ID 4793
Cytogenetics 19q13.2
Summary The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
Protein Families Stem cell - Pluripotency, Transcription Factors
Protein Pathways Adipocytokine signaling pathway, B cell receptor signaling pathway, Chemokine signaling pathway, Cytosolic DNA-sensing pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway
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