BPGM (NM_199186) Human Mass Spec Standard

CAT#: PH302105

BPGM MS Standard C13 and N15-labeled recombinant protein (NP_954655)



  View other "BPGM" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description BPGM MS Standard C13 and N15-labeled recombinant protein (NP_954655)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202105
Predicted MW 30 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_954655
RefSeq Size 2121
RefSeq ORF 777
Synonyms DPGM; ECYT8
Locus ID 669
Cytogenetics 7q33
Summary 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
Protein Families Druggable Genome
Protein Pathways Glycolysis / Gluconeogenesis, Metabolic pathways
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