FE65 (APBB1) (NM_001164) Human Mass Spec Standard

CAT#: PH302003

APBB1 MS Standard C13 and N15-labeled recombinant protein (NP_001155)



  View other "FE65" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description APBB1 MS Standard C13 and N15-labeled recombinant protein (NP_001155)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202003
Predicted MW 77 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001155
RefSeq Size 2699
RefSeq ORF 2124
Synonyms FE65; MGC:9072; RIR
Locus ID 322
Cytogenetics 11p15.4
Summary The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Protein Families Transcription Factors
Protein Pathways Alzheimer's disease
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