MAL (NM_002371) Human Mass Spec Standard

CAT#: PH301256

MAL MS Standard C13 and N15-labeled recombinant protein (NP_002362)



  View other "MAL" proteins (11)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description MAL MS Standard C13 and N15-labeled recombinant protein (NP_002362)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201256
Predicted MW 16.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002362
RefSeq Size 1153
RefSeq ORF 459
Synonyms MVP17; VIP17
Locus ID 4118
Cytogenetics 2q11.1
Summary The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]
Protein Families Transmembrane
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