GLI1 (NM_005269) Human Mass Spec Standard

CAT#: PH301110

GLI1 MS Standard C13 and N15-labeled recombinant protein (NP_005260)



  View other "GLI1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description GLI1 MS Standard C13 and N15-labeled recombinant protein (NP_005260)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201110
Predicted MW 117.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005260
RefSeq Size 3618
RefSeq ORF 3318
Synonyms GLI; PAPA8; PPD1
Locus ID 2735
Cytogenetics 12q13.3
Summary This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
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