MATK (NM_139354) Human Mass Spec Standard

CAT#: PH300454

MATK MS Standard C13 and N15-labeled recombinant protein (NP_647611)



  View other "MATK" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description MATK MS Standard C13 and N15-labeled recombinant protein (NP_647611)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200454
Predicted MW 56.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_647611
RefSeq Size 1940
RefSeq ORF 1521
Synonyms CHK; CTK; HHYLTK; HYL; HYLTK; Lsk
Locus ID 4145
Cytogenetics 19p13.3
Summary The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency
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