TRPM7 Human Gene Knockout Kit (CRISPR)

CAT#: KN218043

TRPM7 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit Polyclonal Anti-TRPM7
    • 50 ul

CNY 11,000.00


TRPM7 (Myc-DDK-tagged)-Human transient receptor potential cation channel, subfamily M, member 7 (TRPM7)
    • 10 ug

CNY 18,800.00

Specifications

Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA GFP-puro
Symbol TRPM7
Locus ID 54822
Kit Components

KN218043G1, TRPM7 gRNA vector 1 in pCas-Guide CRISPR vector

KN218043G2, TRPM7 gRNA vector 2 in pCas-Guide CRISPR vector

KN218043-D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001301212, NM_017672, NR_149152, NR_149153, NR_149154
Synonyms ALSPDC; CHAK; CHAK1; LTrpC-7; LTRPC7; TRP-PLIK
Summary This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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