Human Alanyl tRNA synthetase 2 (AARS2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AARS2
Locus ID	57505
Kit Components	GA111543G1, Alanyl tRNA synthetase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111543G2, Alanyl tRNA synthetase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111543G3, Alanyl tRNA synthetase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_020745
Synonyms	AARSL; COXPD8; LKENP; MT-ALARS; MTALARS
Summary	The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]

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