Human AGXT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	AGXT
Locus ID	189
Kit Components	GA100133G1, AGXT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100133G2, AGXT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100133G3, AGXT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_000030, NM_016236
Synonyms	AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6
Summary	This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]

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