TNNI3K (NM_015978) Human Mutant ORF Clone

Specifications

Product Data
Product Name	TNNI3K (NM_015978) Human Mutant ORF Clone
Mutation Description	R244X
Affected Codon#	244
Affected NT#	730
Nucleotide Mutation	TNNI3K Mutant (R244X), Myc-DDK-tagged ORF clone of Homo sapiens TNNI3 interacting kinase (TNNI3K) as transfection-ready DNA
Effect	Potential protein deficiency
Synonyms	CARK; CCDD
Vector	pCMV6-Entry
Tag	Myc-DDK
ACCN	NM_015978
ORF Size	729 bp
Sequence Data	ORF Nucleotide Sequence (showhide) >RC403207 representing NM_015978 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGAAATTATAAATCTAGACCAACCCAAACTTGTACTGATGAATGGAAGAAAAAAGTCAGTGAATCAT ATGTTATCACAATAGAAAGATTAGAAGATGACCTGCAGATCAAGGAAAAAGAACTGACAGAACTAAGGAA TATATTTGGCTCTGATGAAGCCTTCAGTAAAGTCAATTTAAATTACCGCACTGAAAATGGGCTGTCTCTA CTTCATTTATGTTGCATTTGTGGAGGCAAGAAATCACATATTCGAACTCTTATGTTGAAAGGGCTCCGCC CATCTCGACTGACAAGAAATGGATTTACAGCCTTGCATTTAGCAGTTTACAAGGATAATGCAGAATTGAT CACTTCTCTGCTTCACAGTGGAGCTGATATACAGCAGGTTGGATACGGTGGCCTCACTGCCCTCCATATT GCTACAATAGCTGGCCACCTAGAGGCTGCTGATGTGCTGTTGCAACATGGAGCTAATGTCAATATTCAAG ATGCAGTTTTTTTCACTCCATTGCATATTGCAGCGTACTATGGACATGAACAGGTAACTCGCCTTCTTTT GAAATTTGGTGCTGATGTAAATGTAAGTGGTGAAGTTGGAGATAGACCCCTCCACCTAGCATCTGCAAAA GGATTCTTGAATATTGCAAAACTCTTGATGGAAGAAGGCAGCAAAGCAGATGTGAATGCTCAAGATAATG AAGACCATGTCCCACTCCATTTCTGTTCT AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGA TAAGGTTTAA Protein Sequence (showhide) >RC403207 representing NM_015978 Red=Cloning site Green=Tags(s) MGNYKSRPTQTCTDEWKKKVSESYVITIERLEDDLQIKEKELTELRNIFGSDEAFSKVNLNYRTENGLSL LHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHI ATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLASAK GFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCS SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NP_057062
RefSeq Size	729 bp
RefSeq ORF	2508 bp
Locus ID	51086
Domains	pkinase, TyrKc, ANK, S_TKc
Protein Families	Druggable Genome, Protein Kinase
MW	26.7 kDa
Gene Summary	This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology. [provided by RefSeq, Sep 2012]

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