OGDH (NM_001003941) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC224183L2V

  • LentiORF®

Lenti ORF particles, OGDH (mGFP-tagged) - Human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,690.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name OGDH (NM_001003941) Human Tagged ORF Clone Lentiviral Particle
Synonyms AKGDH; E1k; KGD1; OGDC; OGDH2
Vector pLenti-C-mGFP
ACCN NM_001003941
ORF Size 1281 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC224183).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001003941.1
RefSeq Size 1791 bp
RefSeq ORF 1284 bp
Locus ID 4967
Protein Families Druggable Genome
Protein Pathways Citrate cycle (TCA cycle), Lysine degradation, Metabolic pathways, Tryptophan metabolism
MW 48.18 kDa
Gene Summary This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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