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CACNA1F (NM_005183) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC211587L1V
- LentiORF®
-
Lenti ORF particles, CACNA1F (Myc-DDK tagged) - Human calcium channel, voltage-dependent, L type, alpha 1F subunit (CACNA1F), 200ul, >10^7 TU/mL
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CNY 21,660.00
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规格
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Specifications
| Product Data | |
| Product Name | CACNA1F (NM_005183) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AIED; Cav1.4; Cav1.4alpha1; COD3; COD4; CORDX; CORDX3; CSNB2; CSNB2A; CSNBX2; JM8; JMC8; OA2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_005183 |
| ORF Size | 5931 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC211587).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_005183.2, NP_005174.2 |
| RefSeq Size | 6080 bp |
| RefSeq ORF | 5934 bp |
| Locus ID | 778 |
| Protein Families | Druggable Genome, Ion Channels: Calcium, Transmembrane |
| Protein Pathways | Alzheimer's disease, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Cardiac muscle contraction, Dilated cardiomyopathy, GnRH signaling pathway, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Vascular smooth muscle contraction |
| MW | 220.5 kDa |
| Gene Summary | This gene encodes a multipass transmembrane protein that functions as an alpha-1 subunit of the voltage-dependent calcium channel, which mediates the influx of calcium ions into the cell. The encoded protein forms a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Mutations in this gene can cause X-linked eye disorders, including congenital stationary night blindness type 2A, cone-rod dystropy, and Aland Island eye disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2013] |
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